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Select item 85728561.

Secondary basophilic leukemia in Ph-negative myeloid neoplasms: A distinct subset with poor prognosis

Daniela Berger, Karin Bauer, Christoph Kornauth, Susanne Gamperl, Gabriele Stefanzl, Dubravka Smiljkovic, Christian Sillaber, Peter Bettelheim, Paul Knöbl, Ana-Iris Schiefer, Georg Greiner, Renate Thalhammer, Gregor Hoermann, Ilse Schwarzinger, Philipp B. Staber, Wolfgang R. Sperr, Peter Valent

Neoplasia. 2021 Dec; 23(12): 1183–1191. Published online 2021 Oct 31. doi: 10.1016/j.neo.2021.09.010

PMCID:: PMC8572856

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Select item 71158172.

Proposed diagnostic criteria and classification of basophilic leukemias and related disorders

P Valent, K Sotlar, K Blatt, K Hartmann, A Reiter, I Sadovnik, WR Sperr, P Bettelheim, C Akin, K Bauer, TI George, E Hadzijusufovic, D Wolf, J Gotlib, F-X Mahon, DD Metcalfe, H-P Horny, M Arock

Leukemia. Author manuscript; available in PMC 2020 Jul 24.

Published in final edited form as: Leukemia. 2017 Apr 1; 31(4): 788–797. Published online 2017 Jan 16. doi: 10.1038/leu.2017.15

PMCID:: PMC7115817

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Select item 89207223.

Monoblastic leukemia (M5a) with chronic basophilic leukemia in a cat

Tetsuya SHIMODA, Mika TANABE, Yuuki SHOJI, Takuya KANDA, Kouhei KISHIDA, Ai KISHIDA, Atsushi HASHIMOTO, Mako OTSUKA, Akina MIYAMOTO, Tomoko KAWAKITA, Wataru OSHITA, Reijiro HIRAO, Akihisa SUWA

J Vet Med Sci. 2022 Feb; 84(2): 251–256. Published online 2021 Dec 15. doi: 10.1292/jvms.21-0383

PMCID:: PMC8920722

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Select item 92529134.

The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms

Joseph D. Khoury, Eric Solary, Oussama Abla, Yassmine Akkari, Rita Alaggio, Jane F. Apperley, Rafael Bejar, Emilio Berti, Lambert Busque, John K. C. Chan, Weina Chen, Xueyan Chen, Wee-Joo Chng, John K. Choi, Isabel Colmenero, Sarah E. Coupland, Nicholas C. P. Cross, Daphne De Jong, M. Tarek Elghetany, Emiko Takahashi, Jean-Francois Emile, Judith Ferry, Linda Fogelstrand, Michaela Fontenay, Ulrich Germing, Sumeet Gujral, Torsten Haferlach, Claire Harrison, Jennelle C. Hodge, Shimin Hu, Joop H. Jansen, Rashmi Kanagal-Shamanna, Hagop M. Kantarjian, Christian P. Kratz, Xiao-Qiu Li, Megan S. Lim, Keith Loeb, Sanam Loghavi, Andrea Marcogliese, Soheil Meshinchi, Phillip Michaels, Kikkeri N. Naresh, Yasodha Natkunam, Reza Nejati, German Ott, Eric Padron, Keyur P. Patel, Nikhil Patkar, Jennifer Picarsic, Uwe Platzbecker, Irene Roberts, Anna Schuh, William Sewell, Reiner Siebert, Prashant Tembhare, Jeffrey Tyner, Srdan Verstovsek, Wei Wang, Brent Wood, Wenbin Xiao, Cecilia Yeung, Andreas Hochhaus

Leukemia. 2022; 36(7): 1703–1719. Published online 2022 Jun 22. doi: 10.1038/s41375-022-01613-1

PMCID:: PMC9252913

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Select item 108567205.

Approach to Acute Myeloid Leukemia with Increased Eosinophils and Basophils

Stavros Papadakis, Ioannis Liapis, Stefanos I. Papadhimitriou, Emmanouil Spanoudakis, Ioannis Kotsianidis, Konstantinos Liapis

J Clin Med. 2024 Feb; 13(3): 876. Published online 2024 Feb 2. doi: 10.3390/jcm13030876

PMCID:: PMC10856720

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Genomic Subtyping and Therapeutic Targeting of Acute Erythroleukemia

Ilaria Iacobucci, Ji Wen, Manja Meggendorfer, John K. Choi, Lei Shi, Stanley B. Pounds, Catherine L. Carmichael, Katherine E. Masih, Sarah M. Morris, R. Coleman Lindsley, Laura J. Janke, Thomas B. Alexander, Guangchun Song, Chunxu Qu, Yongjin Li, Debbie Payne-Turner, Daisuke Tomizawa, Nobutaka Kiyokawa, Marcus Valentine, Virginia Valentine, Giuseppe Basso, Franco Locatelli, Eric J. Enemark, Shirley K. Y. Kham, Allen E. J. Yeoh, Xiaotu Ma, Xin Zhou, Edgar Sioson, Michael Rusch, Rhonda E. Ries, Elliot Stieglitz, Stephen P. Hunger, Andrew H. Wei, L Bik To, Ian D. Lewis, Richard J. D’Andrea, Benjamin T. Kile, Anna L. Brown, Hamish S. Scott, Christopher N. Hahn, Paula Marlton, Deqing Pei, Cheng Cheng, Mignon L. Loh, Benjamin L. Ebert, Soheil Meshinchi, Torsten Haferlach, Charles G. Mullighan

Nat Genet. Author manuscript; available in PMC 2019 Nov 4.

Published in final edited form as: Nat Genet. 2019 Apr; 51(4): 694–704. Published online 2019 Mar 29. doi: 10.1038/s41588-019-0375-1

PMCID:: PMC6828160

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Select item 45588327.

Acute basophilic leukaemia in a three-month-old calf

Eva-Maria Laabs, Reinhard Mischke, Peter Dziallas, Arianna Maiolini, Andrea Tipold, Barbara Raddatz, Christina Puff, Jürgen Rehage

Acta Vet Scand. 2015; 57(1): 48. Published online 2015 Sep 3. doi: 10.1186/s13028-015-0141-z

PMCID:: PMC4558832

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Select item 71614138.

Hematopoietic Tumors

David M. Vail, Douglas H. Thamm, Julias M. Liptak

Withrow and MacEwen's Small Animal Clinical Oncology. 2019 : 688–772. Published online 2019 Nov 22. doi: 10.1016/B978-0-323-59496-7.00033-5

PMCID:: PMC7161413

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Select item 100496809.

Choosing the Right Cell Line for Acute Myeloid Leukemia (AML) Research

Rafał Skopek, Małgorzata Palusińska, Katarzyna Kaczor-Keller, Rafał Pingwara, Anna Papierniak-Wyglądała, Tino Schenk, Sławomir Lewicki, Artur Zelent, Łukasz Szymański

Int J Mol Sci. 2023 Mar; 24(6): 5377. Published online 2023 Mar 11. doi: 10.3390/ijms24065377

PMCID:: PMC10049680

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Select item 989456610.

Targeting the EIF2AK1 Signaling Pathway Rescues Red Blood Cell Production in SF3B1-Mutant Myelodysplastic Syndromes With Ringed Sideroblasts

Vera Adema, Feiyang Ma, Rashmi Kanagal-Shamanna, Natthakan Thongon, Guillermo Montalban-Bravo, Hui Yang, Scott A. Peslak, Feng Wang, Pamela Acha, Francesc Sole, Pamela Lockyer, Margherita Cassari, Jaroslaw P. Maciejewski, Valeria Visconte, Irene Gañán-Gómez, Yuanbin Song, Carlos Bueso-Ramos, Matteo Pellegrini, Tuyet M. Tan, Rafael Bejar, Jennifer S. Carew, Stephanie Halene, Valeria Santini, Gheath Al-Atrash, Karen Clise-Dwyer, Guillermo Garcia-Manero, Gerd A. Blobel, Simona Colla

Blood Cancer Discov. 2022 Nov 2; 3(6): 554–567. Published online 2022 Aug 3. doi: 10.1158/2643-3230.BCD-21-0220

PMCID:: PMC9894566

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Select item 879809711.

Decitabine as a treatment choice for de novo acute basophilic leukemia: transient response-a case report

Lei Cao, Rong Wang, Yan Wang, Si-Shu Zhao, Hui Yang, Ji Xu, Qi-Qiang Long, Guang-Sheng He, Jian-Yong Li

Transl Cancer Res. 2020 Feb; 9(2): 1288–1293. doi: 10.21037/tcr.2019.12.14

PMCID:: PMC8798097

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Select item 827806912.

Next‐generation sequencing in two cases of de novo acute basophilic leukaemia

Takuya Shimizu, Tadakazu Kondo, Yasuhito Nannya, Mizuki Watanabe, Toshio Kitawaki, Takero Shindo, Masakatsu Hishizawa, Kouhei Yamashita, Seishi Ogawa, Akifumi Takaori‐Kondo

J Cell Mol Med. 2021 Jul; 25(14): 7095–7099. Published online 2021 Jun 16. doi: 10.1111/jcmm.16591

PMCID:: PMC8278069

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Select item 232719413.

Antibody cross-linking of human CD9 and the high-affinity immunoglobulin E receptor stimulates secretion from transfected rat basophilic leukaemia cells

A Higginbottom, I Wilkinson, B McCullough, F Lanza, D O Azorsa, L J Partridge, P N Monk

Immunology. 2000 Apr; 99(4): 546–552. doi: 10.1046/j.1365-2567.2000.00992.x

PMCID:: PMC2327194

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Select item 790374214.

A review of current knowledge of myeloproliferative disorders in the horse

Katy Satué, Juan Carlos Gardon, Ana Muñoz

Acta Vet Scand. 2021; 63: 8. Published online 2021 Feb 23. doi: 10.1186/s13028-021-00573-3

PMCID:: PMC7903742

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Select item 502614715.

Acute myeloid leukemia with basophilic differentiation in a 3-year-old Standardbred gelding

Mary Catherine Furness, Emile Setlakwe, John Sallaway, Darren Wood, Jordan Fromstein, Luis G. Arroyo

Can Vet J. 2016 Oct; 57(10): 1067–1071.

PMCID:: PMC5026147

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Select item 625682116.

Diagnostic Problems in Chronic Basophilic Leukemia

Cavit Çehreli

Turk J Haematol. 2018 Nov; 35(4): 283–289. Published online 2018 Nov 13. doi: 10.4274/tjh.2018.0129

PMCID:: PMC6256821

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Select item 227020817.

Voltage-dependent conductance changes in the store-operated Ca²⁺ current I_CRAC in rat basophilic leukaemia cells

Daniel Bakowski, Anant B Parekh

J Physiol. 2000 Dec 1; 529(Pt 2): 295–306. doi: 10.1111/j.1469-7793.2000.00295.x

PMCID:: PMC2270208

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Select item 226981018.

Ca²⁺ store dynamics determines the pattern of activation of the store-operated Ca²⁺ current I_CRAC in response to InsP₃ in rat basophilic leukaemia cells

Maike D Glitsch, Anant B Parekh

J Physiol. 2000 Mar 1; 523(Pt 2): 283–290. doi: 10.1111/j.1469-7793.2000.t01-2-00283.x

PMCID:: PMC2269810

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Select item 1045720619.

Blastic plasmacytoid dendritic cell neoplasm: a comprehensive review in pediatrics, adolescents, and young adults (AYA) and an update of novel therapies

Branko Cuglievan, Jeremy Connors, Jiasen He, Sajad Khazal, Sireesha Yedururi, Julia Dai, Sofia Garces, Andres E. Quesada, Michael Roth, Miriam Garcia, David McCall, Amber Gibson, Dristhi Ragoonanan, Demetrios Petropoulos, Priti Tewari, Cesar Nunez, Kris M. Mahadeo, Sarah K. Tasian, Adam J. Lamble, Anna Pawlowska, Danielle Hammond, Abhishek Maiti, Fadi G. Haddad, Jayatsu Senapati, Naval Daver, Naseema Gangat, Marina Konopleva, Soheil Meshinchi, Naveen Pemmaraju

Leukemia. 2023; 37(9): 1767–1778. Published online 2023 Jul 14. doi: 10.1038/s41375-023-01968-z

PMCID:: PMC10457206

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Select item 226975520.

Substantial depletion of the intracellular Ca²⁺ stores is required for macroscopic activation of the Ca²⁺ release-activated Ca²⁺ current in rat basophilic leukaemia cells

Leonardo Fierro, Anant B Parekh

J Physiol. 2000 Jan 15; 522(Pt 2): 247–257. doi: 10.1111/j.1469-7793.2000.t01-1-00247.x

PMCID:: PMC2269755

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PMC Images search for basophilic cell leukemia【内科】肿瘤

Figure 2A) Demonstrating hypersegmented basophil (1), basophilic myelocyte (2), giant binuclear basophilic metamyelocyte (3), pyknotic eosinophil and basophil with drum-stick like nuclear sticks (4, 10), normal basophilic metamyelocyte (6), pyknotic myelocyte, metamyelocytes, binuclear basophilic metamyelocyte and basophilic myelocyte (5, 7, 11, 12, 16), agranular and hypogranular metamyelocyte (8, 9), binuclear hypogranular metamyelocyte (13), basophilic myelocyte (14), Pelger-Hüet anomaly (15) and aggregates of mast cells having mixed orange and dark purplish to black color round cytoplasmic granules (17) in accelerated phase of primary chronic basophilic leukemia with mast cell leukemia (Wright’s stain, 100x); B) Showing tryptase activity in the round, brown color of cytoplasmic granules of mast cells demonstrated by immunohistochemical staining for tryptase. (tryptase immunohistochemical staining, 100x); C) Demonstrating black granular cytoplasmic staining by peroxidase stain in myeloperoxidase-positive basophils and absence of staining in aggregates of cells representing myeloperoxidase-negative mast cells in the bone marrow (peroxidase stain, 100x).

Diagnostic Problems in Chronic Basophilic Leukemia

Turk J Haematol. 2018 Nov;35(4):283-289.
Figure 2

Bone marrow aspirate from a dog with acute myeloblastic leukemia. Mononuclear cells predominate and have high N:C ratios and basophilic cytoplasm. Some cells contain discrete vacuoles or coarse pink granules (arrow). A large multinucleated cell (arrowhead) is present and has a high N:C ratio, basophilic cytoplasm containing small vacuoles, and 8 round to oval nuclei. Modified Wright–Giemsa, × 100 objective.

Acute myeloblastic leukemia with associated BCR-ABL translocation in a dog

Vet Clin Pathol. ;41(3):362-368.
Figure 1

Bone marrow morphology of aggressive NK leukemia. A. A typical type III NK cell exhibited basophilic cytoplasm and bizarre nucleus. B. A typical type I NK cell exhibited large granular lymphocyte appearance in bone marrow smear. C. Dyserythropoiesis was shown in the erythroid cells. D. A typical type II NK cell with one hematophagocytic cells were found in the bone marrow smear.

Six cases of aggressive natural killer-cell leukemia in a Chinese population

Int J Clin Exp Pathol. 2014;7(6):3423-3431.
FIG 1.

TCF3-HLF-positive ALL resembles Burkitt leukemia. (A) Bone marrow aspirate smear shows intermediate-sized blasts with moderately condensed chromatin, inconspicuous nucleoli, and basophilic cytoplasm with cytoplasmic vacuoles (Liu's staining; original magnification ×1,000, expanded view of the original image). (B) Immunophenotype showed positivity for CD19, CD10, CD20, CD33, CD79a, Cu, sIgM, and lambda light chain. ALL, acute lymphoblastic leukemia.

TCF3-HLF-Positive Acute Lymphoblastic Leukemia Resembling Burkitt Leukemia: Cell Morphologic and Immunophenotypic Findings

JCO Precis Oncol. 2022;6:e2200236.